![]() University of Texas Wound Classification System grade >0. This study aims to analyze the influence of medical compression therapy on microcirculation in patients with PAD or diabetes mellitus. ![]() On the other hand, the compression therapy itself may hypothetically cause reduced tissue perfusion, especially in patients with PAD and diabetes. One particular aspect is the microcirculation, which is compromised by interstitial edema this may lead to tissue malnutrition. However, the whole field of compression therapy reveals a huge lack of empirical data and measurements within patients at risk. In summary, the current literature regarding compression therapy in patients with diabetes or PAD mostly reports positive results therefore, compression therapy is widely recommended. Furthermore, they reported visual edema reduction as well as general improvement in patients’ well-being. In patients with PAD, Midttun et al 4 investigated the effect of compression therapy on the systolic toe blood pressure, which was not significantly influenced by compression therapy. 1 3 4 In patients with diabetes, Wu et al 5 comparing mild compression (18–25 mm Hg) with no compression, have demonstrated the clinical advantage of compression therapy in terms of decreased edema and increased patient satisfaction. ![]() 1 However, in patients with peripheral arterial disease (PAD) or diabetes mellitus, both increasing with age, the usage of compression therapy is critically discussed. 2 In contrast, medical compression therapy has shown to be highly effective in the treatment as well as in the prevention of leg edema. 1 One type of therapy for such edemas is the medical diuretic therapy, which however can compromise kidney function in certain patients. Leg edema is of great importance especially in the aged population, causing general discomfort to the patient as well as malnutrition at the level of microcirculation, resulting in leg ulcers.
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